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2. LAYOUT OF A MODERN SPECTROMETER

Figure 2.1 Schematic Layout of an NMR
Spectrometer
A modern NMR spectrometer consists of several
circuit that are represented diagramatically in Figure 2.1. The main parts
of the spectrometer are:
1. Magnet
The magnetic field is generated by a coil of
superconducting wire immersed in a dewar of liquid Helium. This is surrounded
by a vacuum chamber which in turn is surrounded by a dewar of liquid Nitrogen.
The central bore of the magnet contains shim coils that are used to adjust
the field homogeneity in the vicinity of the sample
2. Probe
The NMR sample is placed in a probe inside
the magnet which is arranged so that the sample sits at the centre of
the magnetic field. The probe contains a set of wire coils that are used
both to generate the Electro Magnetic Fields of the RF pulses and to detect
the signal induced by the effects of the pulse on the sample. In addition
the probe contains a heating element for temperature stability and may
aslo have a Gradient Coil for applying Magnetic Field Gradients.
3. Lock Circuit
A stable deuterium frequency is generated by a
Frequency Synthesiser. This signal is passed through a Transmitter
which controls the input of the deuterium signal to the probe. The signal
is passed through an Amplifier before going to the probe. Inisde
the magnet assembly the lock circuitry is connected to a feed back loop
mechanism. This detects changes in the resonant frequency of the deuterium
signal and adjusts the magnetic field to compensate for these changes
by changing the current in a solenoid which forms part of the shim system.
4. Transmitter Circuit
The Frequncy for the Observe Channel is generated
by a Frequency Synthesiser. The timing of the pulses in the NMR
experiment is controlled by the Transmitter under the influence
of the Pulse Programmer. The output from the transmitter is fed
through an optional Pulse Shape Unit and then amplified before
passing into the the Probe.
5. Detector Circuit
The signal detected in the coil at the Observe
Frequency is passed through a Preamplifier to increase the signal.
This is then combined with a second frequency generated by the Frequency
Synthesiser in a Mixer. The resulting signal has a frequncy
of ~10 MHz for a 600 MHz spectrometer. This Intermediate Frequency
is then amplified and split into two parts which pass into the Phase
Sensitive Detectors. The detectors are 90[ring] out of phase with
respect to each other. The detectors rectify the input frequency with
the Intermediate Frequency generated by the Frequency Synthesizer
which results in an output with a frequency range of a few kilohertz.
This signal is passed into the Analogue to Digital Converter which
converts the analogue signal into a digital form that can be stored in
the computer.
6. Decoupler Circuit
In principle there can be as many decoupler
circuits as you can afford. They all have essentially the same design,
but it is more usual to pack the first and second decoupler channels with
the many features and to use more basic designs for any additional channels.
The Decoupler circuit again consists of a very stable Frequency Synthesizer
coupled to a Transmitter which are controlled by the Pulse Programmer.
The input signal passes through a Pulse Shaping unit before being
amplified and sent to the probe. Often the Decoupler signal is passed
through a filter to remove any unwanted frequency spikes e.g. Deuterium
that may have been introduced along the way.
7. Gradient Amplifier (Not Shown)
Most modern NMR spectrometers now include Gradient
Amplifiers. These are acoustic amplifiers that can be used to apply a
magnetic field gradient across the sample. These units also come under
the control of the pulse programmer.
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