Welcome
Student Info
Faculty
Research Cores
Contact
Site Map
Search

 

NMR Home
NMR Intro
Policies
Samples
Rates
Documentation
Schedule
NMR Contact
2. LAYOUT OF A MODERN SPECTROMETER

Figure 2.1 Schematic Layout of an NMR Spectrometer

A modern NMR spectrometer consists of several circuit that are represented diagramatically in Figure 2.1. The main parts of the spectrometer are:

1. Magnet
The magnetic field is generated by a coil of superconducting wire immersed in a dewar of liquid Helium. This is surrounded by a vacuum chamber which in turn is surrounded by a dewar of liquid Nitrogen. The central bore of the magnet contains shim coils that are used to adjust the field homogeneity in the vicinity of the sample

2. Probe
The NMR sample is placed in a probe inside the magnet which is arranged so that the sample sits at the centre of the magnetic field. The probe contains a set of wire coils that are used both to generate the Electro Magnetic Fields of the RF pulses and to detect the signal induced by the effects of the pulse on the sample. In addition the probe contains a heating element for temperature stability and may aslo have a Gradient Coil for applying Magnetic Field Gradients.

3. Lock Circuit
A stable deuterium frequency is generated by a Frequency Synthesiser. This signal is passed through a Transmitter which controls the input of the deuterium signal to the probe. The signal is passed through an Amplifier before going to the probe. Inisde the magnet assembly the lock circuitry is connected to a feed back loop mechanism. This detects changes in the resonant frequency of the deuterium signal and adjusts the magnetic field to compensate for these changes by changing the current in a solenoid which forms part of the shim system.

4. Transmitter Circuit
The Frequncy for the Observe Channel is generated by a Frequency Synthesiser. The timing of the pulses in the NMR experiment is controlled by the Transmitter under the influence of the Pulse Programmer. The output from the transmitter is fed through an optional Pulse Shape Unit and then amplified before passing into the the Probe.

5. Detector Circuit
The signal detected in the coil at the Observe Frequency is passed through a Preamplifier to increase the signal. This is then combined with a second frequency generated by the Frequency Synthesiser in a Mixer. The resulting signal has a frequncy of ~10 MHz for a 600 MHz spectrometer. This Intermediate Frequency is then amplified and split into two parts which pass into the Phase Sensitive Detectors. The detectors are 90[ring] out of phase with respect to each other. The detectors rectify the input frequency with the Intermediate Frequency generated by the Frequency Synthesizer which results in an output with a frequency range of a few kilohertz. This signal is passed into the Analogue to Digital Converter which converts the analogue signal into a digital form that can be stored in the computer.

6. Decoupler Circuit
In principle there can be as many decoupler circuits as you can afford. They all have essentially the same design, but it is more usual to pack the first and second decoupler channels with the many features and to use more basic designs for any additional channels. The Decoupler circuit again consists of a very stable Frequency Synthesizer coupled to a Transmitter which are controlled by the Pulse Programmer. The input signal passes through a Pulse Shaping unit before being amplified and sent to the probe. Often the Decoupler signal is passed through a filter to remove any unwanted frequency spikes e.g. Deuterium that may have been introduced along the way.

7. Gradient Amplifier (Not Shown)
Most modern NMR spectrometers now include Gradient Amplifiers. These are acoustic amplifiers that can be used to apply a magnetic field gradient across the sample. These units also come under the control of the pulse programmer.


Previous Top Contents Next

 


The University of Colorado Health Sciences Center is committed to equal opportunity and affirmative action.



Website Manager