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Biophysics Core Handbook
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ExPASy
Molecular
Biology
Server |
ExPASy Molecular
Biology Server
The ExPASy (Expert Protein Analysis System) proteomics
server of the Swiss
Institute of Bioinformatics (SIB). This server is dedicated
to the analysis of protein sequences and structures as well
as 2-D PAGE.
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ProtParam
tool
A tool for computating various physical and chemical parameters
for a given protein stored in SWISS-PROT or TrEMBL or for
a user entered sequence. The computed parameters include the
molecular weight, theoretical pI, amino acid composition,
atomic composition, extinction coefficient, estimated half-life,
instability index, aliphatic index and grand average of hydropathicity
(GRAVY). (References).
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CLAMP
Software |
CLAMP
Software
A software program designed to interpret complex interactions
recorded on biosensors. It combines numerical integration
and non linear global curve fitting routines.
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Protein
Interaction
Facility |
Protein
Interaction Facility
David Myszka, Director. Some information about analytical
ultracentrifugation, titration calorimetry and optical biosensors
(Biacore).
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Unit
Conversion |
Unit Conversions
Temperature, length, energy, pressure, volume, density,
specific volume, specific heat (entropy), enthalpy, thermal
conductivity, viscosity, and coefficient of heat transfer
conversions. Just enter a number and we will convert it for
you!
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Quadratic
Formula
Solver |
Quadratic
Formula Solver
Enter your coefficients and receive the answers!
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C
O
N
S
T
A
N
T
S
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CONSTANT
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VALUE
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UNIT
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| Avogadro constant |
6.022045 * 1023 |
mol-1 |
| Boltzmann constant |
1.380662 * 10-23 |
J mol-1 K-1 |
|
3.298 * 10-24
|
cal mol-1 K-1 |
| Electronic charge |
1.602 * 10-19 |
C |
| Faraday constant |
96,485 |
C mol-1 |
| Molar gas constant |
8.31441
|
J mol-1 K-1
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| |
0.082057 * 10-3
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m3 atm
mol-1 K-1
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| |
1.987 |
cal mol-1 K-1 |
| Plank's constant |
6.626176 * 10-34 |
J s |
| Velocity of light |
2.998 * 108 |
m s-1 |
| Base of natural logarithms |
2.7183 |
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| Pi |
3.1416 |
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| More information |
E. R. Cohen & N. B. Taylor,
J. Phys. Chem. Ref. Data, vol 2(4), 1973. |
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| Periodic
Table |
Link to the Periodic
Table of Elements. |
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Math
and
Statistics |
Dave's
Math Tables.
GraphPad.
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S
I
U
N
I
T
S
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1012 |
tera
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T |
| 109 |
giga |
G |
106
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mega
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M |
103
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kilo
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k |
102
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hecto
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h |
10
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deca
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da |
10-1
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deci
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d |
10-2
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centi
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c |
10-3
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milli
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m |
10-6
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micro
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µ |
10-9
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nano
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n |
10-12
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pico
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p |
10-15
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femto
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f |
| 10-18 |
atto |
a |
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Circular
Dichroism |
CD 222:208 ratio 1.10 => Coiled coil
CD 222:208 ratio 0.90 => Helix
Molar Ellipticity Online
Conversion
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Thermo-
dynamics
of Protein
Unfolding
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| Protein |
pH
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Delta H°
(kcal mol-1)
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Delta S°
(kcal K-1 mol-1)
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Trypsin
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2.0
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67.6
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213
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Soybean trypsin inhibitor
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3.0
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57.3
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180
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Chymotrypsinogen
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2.0
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99.6
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316
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Chymotrypsinogen
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3.0
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143
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432
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K.J. Laidler, The Chemical Kinetics of Enzyme Actions,
1st ed. Oxford: Clarendon Press, 1958, pp. 354-8.
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| NIST |
National
Institute of Standards and Technology
Elemental data index, physical constants, atomic spectroscopic
data, molecular spectrscopic data, ionization data, x-ray
and gamma-ray data, radiation dosimetry data, nuclear physics
data, etc.
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| Cinemato-graphy |
Reflexive
Film
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