The Biophysics Core Facility is a user facility owned and operated by The Program in Biomolecular Structure at the University of Colorado Health Sciences Center. We opened our doors in early 2001 and have since served a wide variety of researchers on diverse projects in both academia and industry.

We currently have resources to study biomolecular structure and thermodynamics with Biacore surface plasmon resonance phenomonen, CD/ORD, ITC, DSC, fluorescence spectroscopy, and analytical ultracentrifugation (AUC). Mass spectroscopy, LC/MS/MS, HPLC, amino acid analysis are also available.

The Facility provides professional collaborations, training, and instrument time to researchers associated with both nonprofit organizations and private institutions.  After a user is trained, they may use the instruments independently.  Please contact us if you would like the Biophysics Core Staff to run or analyze your samples.

The Biophysics Core Staff are available to train users on each of the instruments located in the core.  We offer one-on-one and group training to those interested in operating the instruments.  Every user must be trained on each instrument before they are allowed independent use.  There will be a one-time charge for training each individual per machine.  After the user is trained, instrument user fees will be assessed.  All fees associated with training and instrument use are listed on the Rates and Policies page.

All scheduling is done with the online calendar. After you are trained to operate an instrument, you may request an account from Brooke Hirsch. Priority is generally on a first-scheduled first-served basis. Users must sign up for an instrument at least 48 hours in advance. Similarly, users must cancel reservations at least 48 hours in advance. If a user fails to cancel an instrument reservation 48 hours before the reserved start time, a charge will be accessed for instrument time.