Molecular Structure

   
Assistant Professor of Cellular & Structural Biology

  • Studies of glycoprotein-protein interaction
  • The specificity of oligosaccharide-protein interactions in the brain
  • Fundamental aspects of glycoprotein construction, and the flexibility of the system for generating variation in oligosaccharide structures in different cell types
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    Associate Professor of Pharmacology

  • X-ray crystallography of protein-protein, protein-ligand, and protein-DNA complexes
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    Professor, Biochemistry & Molecular Genetics
    Director, Program in Biomolecular Structure
    John Stewart Endowed Chair, Peptide Chemistry

  • Determination of the NMR structure of domains of the motor protein dynoin
  • Determination of the X-ray structures of monomeric pilin proteins for designing peptide vaccines
  • Determination of the X-ray structures of two-stranded coiled-coil protein
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    Assistant Professor of Pharmacology

  • Mechanism of alcohol actions
  •    
    Assistant Professor of Biochemistry and Molecular Genetics

  • High resolution structure determination of IRES RNA
  • X-ray crystallography of RNA-protein complexes
  • The global architecture of translation initiation macromolecular assemblies
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    Assistant Professor of Pharmacology

  • Three-dimensional structures of proteins implicated in cancer, Muscular Dystrophy, Schizophrenia, Lupus erythematosus, Aarskog syndrome and other human diseases by NMR spectroscopy
  • Structures and dynamics of membrane-associated proteins
  • Membrane anchoring by phosphoinositide-binding domains
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    Assistant Professor of Biochemistry and Molecular Genetics

  • X-ray crystallographic and biochemical studies of protein, protein/protein complex, and protein/RNA complexes involved in pre-mRNA splicing