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Brad
K. Bendiak, Ph.D.
Assistant Professor of Cellular
& Structural Biology
- studies of glycoprotein-protein interaction;
- the specificity of oligosaccharide-protein interactions
in the brain;
- fundamental aspects of glycoprotein construction, and
the flexibility of the system for generating variation in
oligosaccharide structures in different cell types.
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Mair
E. A. Churchill, Ph.D.
Associate Professor of Pharmacology
- x-ray crystallography of protein-protein, protein-ligand,
and protein-DNA complexes
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Robert
Hodges, Ph.D., F.R.S.C.
Professor, Biochemistry & Molecular
Genetics
Director, Program in Biomolecular Structure
John Stewart Endowed Chair, Peptide Chemistry
- determination
of the NMR structure of domains of the motor protein dynoin;
- determination of the X-ray structures
of monomeric pilin proteins for designing peptide vaccines;
- determination of the X-ray structures
of two-stranded coiled-coil protein
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David
N.M. Jones, Ph.D.
Assistant Professor of Pharmacology
- mechanism of alcohol actions
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Jeffrey
S. Kieft, Ph.D.
Assistant Professor of Biochemistry
and Molecular Genetics
- high resolution structure determination
of IRES RNA;
- x-ray crystallography of RNA-protein complexes;
- the global architecture of translation initiation macromolecular
assemblies
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Tatiana
G. Kutateladze, Ph.D.
Assistant Professor of Pharmacology
- three-dimensional structures of proteins implicated in
cancer, Muscular Dystrophy, Schizophrenia, Lupus erythematosus,
Aarskog syndrome and other human diseases by NMR spectroscopy;
- structures and dynamics of membrane-associated proteins;
- membrane anchoring by phosphoinositide-binding domains
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David
Osguthorpe, Ph.D.
Associate Professor and Director
of the Computational Biology Division
- protein structure prediction;
- conformational behavior of peptide hormones, ligand binding
to proteins, transmembrane protein modeling, membrane simulations
and protein thermostability
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Rui
Zhao , Ph.D.
Assistant Professor of Biochemistry
and Molecular Genetics
- X-ray crystallographic and biochemical studies of protein,
protein/protein complex, and protein/RNA complexes involved
in pre-mRNA splicing
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