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Brad
K. Bendiak, Ph.D.
Assistant Professor of Cellular &
Structural Biology
- regulation of glycoprotein oligosaccharide biosynthesis
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Mair
E. A. Churchill, Ph.D.
Associate Professor of Pharmacology
- protein-DNA interactions and DNA chaperones;
- macromolecular interactions;
- enzymatic mechanism
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Frank
Frerman, Ph.D.
Professor of Pediatrics
Professor of Cell and Structural Biology
- flavoproteins and iron-sulfur proteins;
- inherited metabolic diseases
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Robert
Hodges, Ph.D., F.R.S.C.
Professor, Biochemistry & Molecular
Genetics
Director, Program in Biomolecular Structure
John Stewart Endowed Chair, Peptide Chemistry
- prediction of folding, stability and
structure of proteins from amino acid sequence using tropomyosin
and de novo designed proteins;
- de novo design of templates for generating
conformation-specific antibodies that recognize a-helices
in proteins;
- development of high-performance liquid
chromatography and capillary electrophoresis methodology
for separation of peptides and proteins;
- development of conformational-specific
combinatorial peptide libraries for drug discovery.
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David
N.M. Jones, Ph.D.
Assistant Professor of Pharmacology
- determinants of alcohol binding sites in proteins;
- structure-functions relationships in proteins
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Jeffrey
S. Kieft, Ph.D.
Assistant Professor of Biochemistry
and Molecular Genetics
- the mechanism of internal ribosomal entry;
- RNA-protein recognition strategies
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Tatiana
G. Kutateladze, Ph.D.
Assistant Professor of Pharmacology
- molecular mechanisms of protein-protein and protein-phospholipid
interactions;
- design of membrane mimetic systems for NMR;
- development of quantitative methods for determining the
orientation of proteins within membranes
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