Nichole Reisdorph, Ph.D.
Molecular Biology
Mass Spectrometry and Proteomics
- integrate proteomics, bioinformatics and clinical studies
in order to elucidate the biochemical basis of immunosuppressant
toxicity and obtain a comprehensive biomarker profile for nephrotoxicity
following treatment with immunosuppressants.
Biochemistry - Protein digests;
protein overexpression, purification, characterization; immunoprecipitation;
antibody purification; molecular cloning, cellular transformation.
Selected Publications
1. Reisdorph, N.A. & Small, G.D. (2004) The CPH1 gene of
Chlamydomonas encodes two forms of cryptochrome whose levels are
controlled by light-induced proteolysis. Plant Physiology, 134:1546-1554.
2. Kriwacki, R., Reisdorph, N., Siuzdak, G. (2004) Protein structure
characterization with mass spectrometry. Spectroscopy, 18:37-47.
3. Reisdorph N., Thomas J.J., Katpally U., Chase E., Harris K.,
Siuzdak G., Smith T.J. (2003) Human rhinovirus capsid dynamics
is controlled by canyon flexibility. Virology, 314:34-44.
Bibliography