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John Kappler, Ph.D.
Publications, 2001
1. Kedl, R.M., B.C. Schaefer, J.W. Kappler, and P. Marrack. 2002. T cells down-modulate
peptide-MHC complexes on APCs in vivo. Nat Immunol 3:27-32.
2. Wilson, N., D. Fremont, P. Marrack, and J. Kappler. 2001. Mutations changing
the kinetics of class II MHC peptide exchange. Immunity 14:513-522.
3. Schaefer, B.C., T.C. Mitchell, J.W. Kappler, and P. Marrack. 2001. A novel
family of retroviral vectors for the rapid production of complex stable cell lines.
Anal Biochem 297:86-93.
4. Mitchell, T.C., D. Hildeman, R.M. Kedl, T.K. Teague, B.C. Schaefer, J. White,
Y. Zhu, J. Kappler, and P. Marrack. 2001. Immunological adjuvants promote activated
T cell survival via induction of Bcl-3. Nat Immunol 2:397-402.
5. Marrack, P., J. Bender, M. Jordan, W. Rees, J. Robertson, B.C. Schaefer,
and J. Kappler. 2001. Major histocompatibility complex proteins and TCRs: do they
really go together like a horse and carriage? J Immunol 167:617-621.
6. Marrack, P., J. Kappler, and B.L. Kotzin. 2001. Autoimmune disease: why
and where it occurs. Nat Med 7:899-905.
7. Lang, P., J.C. Stolpa, B.A. Freiberg, F. Crawford, J. Kappler, A. Kupfer,
and J.C. Cambier. 2001. TCR-induced transmembrane signaling by peptide/MHC class
II via associated Ig-alpha/beta dimers. Science 291:1537-1540.
8. Ku, C.C., J. Kappler, and P. Marrack. 2001. The growth of the very large
CD8+ T cell clones in older mice is controlled by cytokines. J Immunol 166:2186-2193.
9. Kersh, G.J., M.J. Miley, C.A. Nelson, A. Grakoui, S. Horvath, D.L. Donermeyer,
J. Kappler, P.M. Allen, and D.H. Fremont. 2001. Structural and functional consequences
of altering a peptide MHC anchor residue. J Immunol 166:3345-3354.
10. Kedl, R.M., M. Jordan, T. Potter, J. Kappler, P. Marrack, and S. Dow. 2001.
CD40 stimulation accelerates deletion of tumor-specific CD8(+) T cells in the
absence of tumor-antigen vaccination. Proc Natl Acad Sci U S A 98:10811-10816.
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