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Robert L. Garcea, M.D.
Publications
- Garcea RL, Imperiale MJ. Simian virus 40 infection of
humans.
J Virol. 2003 May;77(9):5039-45.
- Finnen RL, Erickson KD, Chen XS, Garcea RL. Interactions
between Papillomavirus L1 and L2 Capsid Proteins. J Virol. 2003
Apr;77(8):4818-26.
- Ohlschlager P, Osen W, Dell K, Faath S, Garcea RL, Jochmus
I, Muller M, Pawlita M, Schafer K, Sehr P, Staib C, Sutter G,
Gissmann L. Human papillomavirus type 16 l1 capsomeres induce
l1-specific cytotoxic T lymphocytes and tumor regression in C57BL/6
mice.
J Virol. 2003 Apr;77(8):4635-45.
- Garcea RL. SV40: A human pathogen? Dis Markers. 2001;17(3):149-51.
Review.
- Malkin D, Chilton-MacNeill S, Meister LA, Sexsmith E, Diller
L, Garcea RL. Tissue-specific expression of SV40 in tumors
associated with the Li-Fraumeni syndrome. Oncogene. 2001 Jul 27;20(33):4441-9.
- Yuan H, Estes PA, Chen Y, Newsome J, Olcese VA, Garcea RL,
Schlegel R. Immunization with a pentameric L1 fusion protein protects
against papillomavirus infection. J Virol. 2001 Sep;75(17):7848-53.
- Chen XS, Casini G, Harrison SC, Garcea RL. Papillomavirus
capsid protein expression in Escherichia coli: purification and
assembly of HPV11 and HPV16 L1. J Mol Biol. 2001 Mar 16;307(1):173-82.
- Lednicky JA, Garcea RL. Detection of SV40 DNA sequences
in human tissue. Methods Mol Biol. 2001;165:257-67. No abstract
available.
- Chen XS, Garcea RL, Goldberg I, Casini G, Harrison SC.
Structure of small virus-like particles assembled from the L1
protein of human papillomavirus 16. Mol Cell. 2000 Mar;5(3):557-67.
- Szomolanyi-Tsuda E, Brien JD, Dorgan JE, Welsh RM, Garcea
RL. The role of CD40-CD154 interaction in antiviral T cell-
independent IgG responses. J Immunol. 2000 Jun 1;164(11):5877-82.
- Schwartz R, Garcea RL, Berger B. "Local rules"
theory applied to polyomavirus polymorphic capsid assemblies.
Virology. 2000 Mar 15;268(2):461-70.
- Wang J, Garcea RL. Simian virus 40 DNA sequences in human
brain and bone tumours. Dev Biol Stand. 1998;94:13-21. Review.
- Szomolanyi-Tsuda E, Le QP, Garcea RL, Welsh RM. T-Cell-independent
immunoglobulin G responses in vivo are elicited by live-virus
infection but not by immunization with viral proteins or virus-like
particles. J Virol. 1998 Aug;72(8):6665-70.
- Rose RC, White WI, Li M, Suzich JA, Lane C, Garcea RL.
Human papillomavirus type 11 recombinant L1 capsomeres induce
virus-neutralizing antibodies. J Virol. 1998 Jul;72(7):6151-4.
- Li M, Beard P, Estes PA, Lyon MK, Garcea RL. Intercapsomeric
disulfide bonds in papillomavirus assembly and disassembly. J
Virol. 1998 Mar;72(3):2160-7.
- Butel JS, Lednicky JA, Stewart AR, Garcea RL, Finegold
MJ. SV40 and human brain tumors. J Neurovirol. 1997 May;3 Suppl
1:S78-9. Review. No abstract available.
- Li M, Cripe TP, Estes PA, Lyon MK, Rose RC, Garcea RL.
Expression of the human papillomavirus type 11 L1 capsid protein
in Escherichia coli: characterization of protein domains involved
in DNA binding and capsid assembly. J Virol. 1997 Apr;71(4):2988-95.
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Carbone M, Rizzo P, Procopio A, Giuliano M, Pass HI, Gebhardt
MC, Mangham C, Hansen M, Malkin DF, Bushart G, Pompetti F, Picci
P, Levine AS, Bergsagel JD, Garcea RL. SV40-like sequences
in human bone tumors. Oncogene. 1996 Aug 1;13(3):527-35.
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Li, M., Cripe, T. P., Estes, P. A., Lyon, M. K., Rose, R.
C., and Garcea, R. L. Expression
of the human papillomavirus type 11 L1 capsid protein in Escherichia
coli: Characterization of protein domains involved in DNA binding
and capsid assembly. J. Virol. 1997; 71:2988-2995.
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Li. M., Beard, P., Estes, P.A., Lyon, M.K., and Garcea,
R.L. Intercapsomeric disulfide bonds in papillomavirus
assembly and disassembly. J. Virol. 1998; 72:2160-2167.
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Rose, R.C., White, W., Li, M., Suzich, J., Lane, C., and Garcea,
R.L. Human papillomavirus type 11 (HPV-11) recombinant
L1 capsomeres induce virus-neutralizing antibodies. J. Virol.
1998; 72:6151-6154.
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Szomolanyi-Tsuda, E., Le, Q.P.,
Garcea, R.L., and Welsh, R.M. T cell-independent immunoglobulin
G responses in vivo are elicited by live-virus infection, but
not by immunization with viral proteins or virus-like particles.
J. Virol. 1998; 72:6665-6670.
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Schwartz, R., Garcea, R.L.,
and Berger, B. Local Rules theory applied to polyomavirus
polymorphic capsid assemblies. Virology 2000; 268:461-470.
-
Chen, X., Garcea, R.L.,
Casini, G., Goldberg, I., and Harrison, S.C. Structure of small
virus-like particles assembled from the L1 protein of human
papillomavirus 16. Mol. Cell 2000; 5:557-567.
-
Szomolanyi-Tsuda, E., Brien, J.D., Dorgan, J.E., Welsh, R.M.,
and Garcea, R.L. The role of CD40-CD154 interaction in antiviral
T cell-independent IgG responses. J. Immunol. 2000; 164:5877-82.
-
Szomolanyi-Tsuda, E., Brien, J.D., Dorgan, J.E.,
Garcea, R.L., Woodland, R.T., and Welsh, R.M. Antiviral
T cell-independent type 2 antibody responses induced in vivo
in the absence of T and NK cells. Virology 2001; 280:160-168.
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Chen, X., Casini, G. Harrison, S.C., and Garcea,
R.L. Papillomavirus capsid protein expression in Escherichia
coli: Purification and assembly of HPV11 and HPV16 L1 J. Mol.
Bio. 2001: 307: 173-182.
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Malkin, D., Chilton-MacNeill, S., Meister, L.A., Sexsmith,
E., Diller, L., and Garcea, R.L.
Tissue-specific expression of SV40 virus and mechanisms of loss
of heterozygosity of p53 in a child with Li-Fraumeni Syndrome.
Oncogene 2001; 20: 4441-4449.
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Yuan, H., Estes, P.A., Chen, Y., Newsome, J., Olcese, V.A.,
Garcea, R.L., and Schlegel, R. Immunization with a pentameric
L1 fusion protein protects against papillomavirus infection.
J. Virol. 2001; 75: 7848-7853.
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