Mair E. A. Churchill, Ph.D.

Publications

1. Churchill ME. Watching flipping junctions. Nat Struct Biol 2003 Feb;10(2):73-5
   

2. Melvin VS, Roemer SC, Churchill ME, Edwards DP.
   The C-terminal extension (CTE) of the nuclear hormone receptor DNA binding domain determines interactions and functional response to the HMGB-1/-2 co- regulatory proteins. J Biol Chem 2002 Jul 12;277(28):25115-24
   

3. W.T. Watson, T. D. Minogue, D. L. Val, S. B. von Bodman, and M.E.A. Churchill (2002) "Structural Basis and Specificity of Acyl-homoserineLactone Signal Production in Bacterial Quorum Sensing" Mol Cell 2002 Mar;9(3):685-94

4. F.V. Murphy IV & M.E.A. Churchill "Non-sequence-specific DNA recognition: a structural perspective." Invited Mini-Review (2000) Structure 8, R83-89.
   

5. W.T. Watson, F.V. Murphy IV, T.A. Gould, P. Jambeck, D. L. Val, J. E. Cronan,Jr., S. Beck von Bodman, and M.E.A. Churchill "Crystallization and Rhenium MAD Phasing of the Acyl-homoserinelactone Synthase EsaI." (2001) Acta Crystallographica, D57, 1945-1949.

6. Scavetta RD, Thomas CB, Walsh MA, Szegedi S, Joachimiak A, Gumport RI, Churchill ME. Structure of RsrI methyltransferase, a member of the N6-adenine beta class of DNA methyltransferases. Nucleic Acids Res. 2000 Oct 15;28(20):3950-61.

7. Dow LK, Jones DN, Wolfe SA, Verdine GL, Churchill ME. Structural studies of the high mobility group globular domain and basic tail of HMG-D bound to disulfide cross-linked DNA. Biochemistry. 2000 Aug 15;39(32):9725-36.

8. Murphy FV 4th, Churchill ME. Nonsequence-specific DNA recognition: a structural perspective. Structure Fold Des. 2000 Apr 15;8(4):R83-9. Review.

9. Murphy FV 4th, Sweet RM, Churchill ME. The structure of a chromosomal high mobility group protein-DNA complex reveals sequence-neutral mechanisms important for non-sequence-specific DNA recognition. EMBO J. 1999 Dec 1;18(23):6610-8.

10. Murphy FV 4th, Sehy JV, Dow LK, Gao YG, Churchill ME. Co-crystallization and preliminary crystallographic analysis of the high mobility group domain of HMG-D bound to DNA. Acta Crystallogr D Biol Crystallogr. 1999 Sep;55 ( Pt 9):1594-7.

11. Churchill ME, Changela A, Dow LK, Krieg AJ. Interactions of high mobility group box proteins with DNA and chromatin. Methods Enzymol. 1999;304:99-133. No abstract available.

12. Kuo MH, Zhou J, Jambeck P, Churchill ME, Allis CD. Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo. Genes Dev. 1998 Mar 1;12(5):627-39.

13. Balaeff A, Churchill ME, Schulten K. Structure prediction of a complex between the chromosomal protein HMG-D and DNA. Proteins. 1998 Feb 1;30(2):113-35.

14. Dow LK, Changela A, Hefner HE, Churchill ME. Oxidation of a critical methionine modulates DNA binding of the Drosophila melanogaster high mobility group protein, HMG-D. FEBS Lett. 1997 Sep 15;414(3):514-20.

15. Lampe DJ, Churchill ME, Robertson HM. A purified mariner transposase is sufficient to mediate transposition in vitro. EMBO J. 1996 Oct 1;15(19):5470-9.

16. Churchill ME. The latest on DNA form and function. Chem Biol. 1996 Sep 1;3(9):729-30. No abstract available. [Record as supplied by publisher]

17. Churchill ME, Jones DN, Glaser T, Hefner H, Searles MA, Travers AA. HMG-D is an architecture-specific protein that preferentially binds to DNA containing the dinucleotide TG.

18. Wolfe SA, Ferentz AE, Grantcharova V, Churchill ME, Verdine GL. Modifying the helical structure of DNA by design: recruitment of an architecture-specific protein to an enforced DNA bend. Chem Biol. 1995 Apr;2(4):213-21.

19. Churchill ME, Jones DN, Glaser T, Hefner H, Searles MA, Travers AA. HMG-D is an architecture-specific protein that preferentially binds to DNA containing the dinucleotide TG. EMBO J. 1995 Mar 15;14(6):1264-75.

20. Churchill ME, Stura EA, Pinilla C, Appel JR, Houghten RA, Kono DH, Balderas RS, Fieser GG, Schulze-Gahmen U, Wilson IA. Crystal structure of a peptide complex of anti-influenza peptide antibody Fab 26/9. Comparison of two different antibodies bound to the same peptide antigen. J Mol Biol. 1994 Aug 26;241(4):534-56.

21. Jones DN, Searles MA, Shaw GL, Churchill ME, Ner SS, Keeler J, Travers AA, Neuhaus D. The solution structure and dynamics of the DNA-binding domain of HMG-D from Drosophila melanogaster. Structure. 1994 Jul 15;2(7):609-27.

22. Ner SS, Travers AA, Churchill ME. Harnessing the writhe: a role for DNA chaperones in nucleoprotein-complex formation. Trends Biochem Sci. 1994 May;19(5):185-7. Review. No abstract available.

23. Travers AA, Ner SS, Churchill ME. DNA chaperones: a solution to a persistence problem? Cell. 1994 Apr 22;77(2):167-9. Review. No abstract available.

24. Churchill ME, Gemmell MA, Woloschak GE. Detection of retinoblastoma gene deletions in spontaneous and radiation-induced mouse lung adenocarcinomas by polymerase chain reaction. Radiat Res. 1994 Mar;137(3):310-6.