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John Cambier, Ph.D.
Publications 2001 and Books
214) Benschop, R.J., K. Aviszus, X. Zhang, T. Manser, J.C. Cambier, and L.J.
Wysocki. 2001. Activation and anergy in bone marrow B cells of a novel immunoglobulin
transgenic mouse that is both hapten-specifc and autoreactive. Immunity. 14:33-43.
215) Lang, P., Stolpa, J.C., Freiberg, B.A., Crawford, F., Kappler, J., Kupfer,
A., Cambier, J.C. 2001. TCR-induced transmembrane signaling by peptide/MHC class
II via associated Ig-a/b dimers. Science. 291:1537-1540.
216) Brauweiler, A., Tamir, I., Marschner, S., Helgason, C.D., and Cambier, J.C. 2001. Partially distinct molecular mechanisms mediate inhibitory FcgRIIB
signaling in resting and activated B cells. J. Immunol. 167:204-211.
217) Kraus, Pao, L., Reichlin, Hu, Conono, Cambier, J.C., Nussenzweig and Rajewsky.
2001. Interference with Iga ITAM Phosphorylation Modulates or Blocks B Cell Development,
Depending on the Availability of an Igb Cytoplasmic Tail. Journal of Experimental
Medicine. 194:455-70..
218) Ott, V., Fong, D.C., and Cambier, J.C. 2001. Fcg-RIIB as a potential molecular
target for intravenous gamma globulin therapy. Journal of Allergy and Clincial
Immunology. 108:S95-S98
219) Benschop, R.J., Brandl, E., Chan, A.C. and Cambier, J.C. 2001.
Unique signaling properties of B cell antigen receptor in mature and immature
B cells: implications for tolerance and activations. The Journal of Immunology.
167:4172-4179.
220) Jensen, W.A., Marschner, S., Ott, V.L. and Cambier, J.C. 2001. FcgRIIB-mediated
inhibition of T cell receptor signal transduction involves phosphorylation of
SHIP, dephosphorylation of LAT, and inhibition of calcium mobilization. Biochem
Soc Trans. 2001 Dec;29(6):840-6.
221) Marschner, S. and Cambier, J.C. 2001. gp120 induced inhibitory CD4 signaling
is mediated by the inositol 5-phosphatase SHIP and the RasGap adaptor Dok. (submitted
for publication)
222) Pan, P-Y., Giallourakis, C.C., Coggeshall, K.M., Cambier, J.C., Rothman,
P.B. Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM) of the IL-4 receptor
associates with SH2-containing phosphates and regulates IL-4 induced proliferation.
(submitted for publication).
223) Bannish, G., Fuentes-Panana, E.M., Cambier, J.C., Pear, W.S. and Monroe,
J.G. 2001. Ligand-Independent signaling functions for the B lymphocyte antigen
receptor and their role in positive selection during B lymphopoiesis. J. Ex. Med.
(in press)
224) Marschner, S., Hilnig, T., Cambier, J.C., and Finkel, T.H. 2001. Ligation
of human CD4 interferes with activation of resting T cells. Immunology Letters.
(in press)
225) Chumley, M.J., DalPorto, J.M., and Cambier, J.C. 2001. The Unique Antigen
Receptor Signaling Phenotype of B-1 B Cells is Locale Dependent and Antigen Induced.
The Journal of Immunology. (submitted for publication)
Books:
230) Cambier, J.C. 1985. B-lymphocyte Differentiation. J. Cambier, Ed., Uniscience
Series, CRC Press, Boca Raton, FL.
Mond, J.J., J.C. Cambier and A. Weiss. 1989. Regulation of cell growth
and activation. Advances in Regulation of Cell Growth, Raven Press, Vol. 1.
Mond, J.J., J.C. Cambier and A. Weiss. 1990. Cell Activation: Genetic
Approaches. Advances in Regulation of Cell Growth, Raven Press, Vol. 2.
Cambier, J.C. 1990. Ligands, Receptors and Signal Transduction in Regulation
of Lymphocyte Function. American Society for Microbiology, Washington, D.C.
Cambier, J.C. 1996. Lymphocyte Activation and Effector Functions. Current
Opinion in Immunology, F Alt and P Marrack Eds. Vol. 8.
Publications
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