David L. Bain, Ph.D.

Publications

1. McManaman JL and Bain DL. "Structural and conformational analysis of the oxidase to dehydrogenase conversion of xanthine oxidoreductase." J Biol Chem. 2002 277(24):21261-8

2. Bain DL, Franden MA, McManaman JL, Takimoto GS, Horwitz KB. The N-terminal region of human progesterone B-receptors: biophysical and biochemical comparison to A-receptors. J Biol Chem. 2001 Jun 29;276(26):23825-31.

3. Bain DL, Berton N, Ortega M, Baran J, Yang Q, Catalano CE. Biophysical characterization of the DNA binding domain of gpNu1, a viral DNA packaging protein. J Biol Chem. 2001 Jun 8;276(23):20175-81.

4. Graham JD, Bain DL, Richer JK, Jackson TA, Tung L, Horwitz KB. Thoughts on tamoxifen resistant breast cancer. Are coregulators the answer or just a red herring? J Steroid Biochem Mol Biol. 2000 Nov 30;74(5):255-9. Review.

5. Graham JD, Bain DL, Richer JK, Jackson TA, Tung L, Horwitz KB. Nuclear receptor conformation, coregulators, and tamoxifen-resistant breast cancer. Steroids. 2000 Oct-Nov;65(10-11):579-84. Review.

6. Bain DL, Franden MA, McManaman JL, Takimoto GS, Horwitz KB. The N-terminal region of the human progesterone A-receptor. Structural analysis and the influence of the DNA binding domain. J Biol Chem. 2000 Mar 10;275(10):7313-20.

7. Graham JD, Bain DL, Richer JK, Jackson TA, Tung L, Horwitz KB. Nuclear receptor conformation, coregulators, and tamoxifen-resistant breast cancer. Steroids. 2000 Oct-Nov;65(10-11):579-84.

8. Myles PS, Bain DL, Johnson F, McMahon R. Is anaesthesia evidence-based? A survey of anaesthetic practice. Br J Anaesth. 1999 Apr;82(4):591-5.

9. Bain DL, Ackers GK. A quantitative cryogenic gel-shift technique for analysis of protein-DNA binding. Anal Biochem. 1998 May 1;258(2):240-5.

10. Perrin MH, Sutton S, Bain DL, Berggren WT, Vale WW. The first extracellular domain of corticotropin releasing factor-R1 contains major binding determinants for urocortin and astressin. Endocrinology. 1998 Feb;139(2):566-70.

11. Jackson TA, Richer JK, Bain DL, Takimoto GS, Tung L, Horwitz KB. The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT. Mol Endocrinol. 1997 Jun;11(6):693-705.

12. Horwitz KB, Jackson TA, Bain DL, Richer JK, Takimoto GS, Tung L. Nuclear receptor coactivators and corepressors. Mol Endocrinol. 1996 Oct;10(10):1167-77. Review.

13. Bain DL, Ackers GK. Self-association and DNA binding of lambda cI repressor N-terminal domains reveal linkage between sequence-specific binding and the C-terminal cooperativity domain. Biochemistry. 1994 Dec 13;33(49):14679-89.

14. Koblan KS, Bain DL, Beckett D, Shea MA, Ackers GK. Analysis of site-specific interaction parameters in protein-DNA complexes. Methods Enzymol. 1992;210:405-25. No abstract available.

15. Lane P, Vichi P, Bain DL, Tritton TR. Temperature dependence studies of adriamycin uptake and cytotoxicity. Cancer Res. 1987 Aug 1;47(15):4038-42.

16. Ostrowski LE, Ahsan A, Suthar BP, Pagast P, Bain DL, Wong C, Patel A, Schultz RM. Selective inhibition of proteolytic enzymes in an in vivo mouse model for experimental metastasis. Cancer Res. 1986 Aug;46(8):4121-8.

17. Graham JD, Bain DL, Richer JK, Jackson TA, Tung L, Horwitz KB. Nuclear receptor conformation, coregulators, and tamoxifen-resistant breast cancer. Steroids. 2000 Oct-Nov;65(10-11):579-84.

18. Bain DL, Franden MA, McManaman JL, Takimoto GS, Horwitz KB. The N-terminal region of the human progesterone A-receptor. Structural analysis and the influence of the DNA binding domain.

19. Myles PS, Bain DL, Johnson F, McMahon R. Is anaesthesia evidence-based? A survey of anaesthetic practice. Br J Anaesth. 1999 Apr;82(4):591-5.

20. Bain DL, Ackers GK. A quantitative cryogenic gel-shift technique for analysis of protein-DNA binding. Anal Biochem. 1998 May 1;258(2):240-5

21. Perrin MH, Sutton S, Bain DL, Berggren WT, Vale WW. The first extracellular domain of corticotropin releasing factor-R1 contains major binding determinants for urocortin and astressin. Endocrinology. 1998 Feb;139(2):566-70.

22. Jackson TA, Richer JK, Bain DL, Takimoto GS, Tung L, Horwitz KB. The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT. Mol Endocrinol. 1997 Jun;11(6):693-705.

23. Horwitz KB, Jackson TA, Bain DL, Richer JK, Takimoto GS, Tung L. Nuclear receptor coactivators and corepressors. Mol Endocrinol. 1996 Oct;10(10):1167-77. Review.