The primary users of the X-ray core facility include Drs. Mair Churchill (Pharmacology), Jeffrey Kieft (Biochemistry and Molecular Genetics), David Jones (Pharmacology), and Rui Zhao (Biochemistry and Molecular Genetics). In addition, these primary users collaborate with Drs. Bob Sclafani, Jessica Tyler, Charles McHenry (Biochemistry and Molecular Genetics), Michael Holers (Immunology), Bob Garcia (Pediatrics), Aleem Siddiqui (Microbiology), Dean Edwards (Pathology), and Heide Ford (Obstetrics & Gynecology) in a variety of research areas. Some recent publications by these users are listed below.

W.T. Watson, T. D. Minogue, Dale L. Val, S. Beck von Bodman, and M.E.A.
Churchill (2002). Structural Basis and Specificity of Acyl-homoserine
lactone Signal Production in Bacterial Quorum Sensing. Molecular Cell, in press.

W.T. Watson, F.V. Murphy IV, T.A. Gould, P. Jambeck, D. L. Val, J. E.
Cronan,Jr., S. Beck von Bodman, and M.E.A. Churchill (2001) Crystallization and Rhenium MAD Phasing of the Acyl-homoserinelactone Synthase EsaI. Acta Crystallographica, D57, 1945-1949.

Szakonyi, G., J. Guthridge, D. Li, K. Young, M. Holers, and X. Chen (2001). Structure of complement receptor type 2 in complex with its ligand c3d. Science 292, 1725-1728.

Chen, X., G. Casini, S.C. Harrison, and R. Garcia (2001). Papillomavirus capsid protein expression in Escherichia coli: purification and assembly of HPV11 and HPV16 L1. J. Mol. Biol. 307, 173-182.

R.D. Scavetta, C.B. Thomas, M.A. Walsh, S. Szegedi, A. Joachimiak, R.I.
Gumport, M.E.A. Churchill (2000). Structure of RsrI methyltransferase, a member of the N6-Adenine b class of DNA methyltransferases. Nucleic Acids Research, 28, 3950-3961.

L.K. Dow, D.N.M. Jones, S.A. Wolfe, G.L. Verdine, and M.E.A. Churchill (2000). Structural Studies of the High Mobility Group Globular Domain and Basic Tail of HMG-D Bound to Disulfide Cross-linked DNA. Biochemistry 39, 9725-9736.

F.V. Murphy IV, R. M. Sweet, & M.E.A. Churchill (1999). The Structure of a Chromosomal High-Mobility-Group Protein-DNA Complex Reveals Sequence-neutral Mechanisms Important for Non-sequence-specific DNA Recognition. EMBO J. 18, 6610-6618.

F.V. Murphy IV, J. V. Sehy, Y.G. Gao, L.K. Dow & M.E.A. Churchill (1999). Co-crystallization and Preliminary Crystallographic Analysis of the HMG
Domain of HMG-D Bound to DNA. Acta Crystallographica D55, 1594-1597.